P0300 Engine Misfire Common Causes

A common reason for check engine light code P3000 misfires, hesitation, and stumble is a corroded ignition coil and/or spark plug wire. This example is from a 3.1L, 3.4L and 3.8L engine.

This is what the coil towers should look like.

Corrosion on this ignition coil and spark plug wire will cause misfires under hard acceleration, or when cruising at a steady speed (45-65 mph) then accelerating to pass. Engine will also misfire at idle on wet, damp mornings. Causes a check engine light code p0300.

What can cause my coil to not have any fire after i replaced the engine.
 Well that depends on the car and engine. Changing the engine would have nothing to do with it unless you did not, or hooked something up incorrectly.